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IL-1β/HMGB1 signalling promotes the inflammatory cytokines release via TLR signalling in human intervertebral disc cells

Inflammation and cytokines have been recognized to correlate with intervertebral disc (IVD) degeneration (IDD), via mediating the development of clinical signs and symptoms. However, the regulation mechanism remains unclear. We aimed at investigating the regulatory role of interleukin (IL)β and high...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Fang, Fang, Jiang, Dianming
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025813/
https://ncbi.nlm.nih.gov/pubmed/27512095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160118
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