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Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

The NF-κB pathway has critical roles in cancer, immunity and inflammatory responses. Understanding the mechanism(s) by which mutations in genes involved in the pathway cause disease has provided valuable insight into its regulation, yet many aspects remain unexplained. Several lines of evidence have...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Scholefield, Janine, Henriques, Ricardo, Savulescu, Anca F., Fontan, Elisabeth, Boucharlat, Alix, Laplantine, Emmanuel, Smahi, Asma, Israël, Alain, Agou, Fabrice, Mhlanga, Musa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025789/
https://ncbi.nlm.nih.gov/pubmed/27586688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12629
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