Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury

Tumor necrosis factor (TNF)-stimulated gene-6 (TSG-6) binds to hyaluronan and can reorganize/stabilize its structure, also enhancing the binding of this glycosaminoglycan to its cell surface receptor, CD44. TSG-6 is rapidly up-regulated in response to inflammatory cytokines protecting tissues from t...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Coulson-Thomas, Vivien J., Lauer, Mark E., Soleman, Sara, Zhao, Chao, Hascall, Vincent C., Day, Anthony J., Fawcett, James W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Glycobiology and Extracellular Matrices
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025681/
https://ncbi.nlm.nih.gov/pubmed/27435674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710673
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