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The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)(6)-NH(2) Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

Neutrophils expressing formyl peptide receptor 2 (FPR2) play key roles in host defense, immune regulation, and resolution of inflammation. Consequently, the search for FPR2-specific modulators has attracted much attention due to its therapeutic potential. Earlier described agonists for this receptor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Holdfeldt, André, Skovbakke, Sarah Line, Winther, Malene, Gabl, Michael, Nielsen, Christina, Perez-Gassol, Iris, Larsen, Camilla Josephine, Wang, Ji Ming, Karlsson, Anna, Dahlgren, Claes, Forsman, Huamei, Franzyk, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025677/
https://ncbi.nlm.nih.gov/pubmed/27422818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736850
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