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Sierra platinum: a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering

BACKGROUND: Histone modifications play an important role in gene regulation. Their genomic locations are of great interest. Usually, the location is measured by ChIP-seq and analyzed with a peak-caller. Replicated ChIP-seq experiments become more and more available. However, their analysis is based...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Müller, Lydia, Gerighausen, Daniel, Farman, Mariam, Zeckzer, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025614/
https://ncbi.nlm.nih.gov/pubmed/27634469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1248-6
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