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Probucol dramatically enhances dihydroartemisinin effect in murine malaria

BACKGROUND: Artemisinin-based combination therapy (ACT) has been adopted as national policy for the first-line treatment in large number of malaria-endemic regions. However, artemisinin-resistant parasites have emerged and are spreading, with slow-cleaning parasites being reported in patients treate...

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Bibliographic Details
Published in:Malar J
Main Authors: Kume, Aiko, Anh, Dang Trinh Minh, Shichiri, Mototada, Ishida, Noriko, Suzuki, Hiroshi
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025592/
https://ncbi.nlm.nih.gov/pubmed/27634686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1532-y
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