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In Papyro Comparison of TMM (edgeR), RLE (DESeq2), and MRN Normalization Methods for a Simple Two-Conditions-Without-Replicates RNA-Seq Experimental Design

In the past 5 years, RNA-Seq has become a powerful tool in transcriptome analysis even though computational methods dedicated to the analysis of high-throughput sequencing data are yet to be standardized. It is, however, now commonly accepted that the choice of a normalization procedure is an import...

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Detalhes bibliográficos
Publicado no:Front Genet
Autor principal: Maza, Elie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025571/
https://ncbi.nlm.nih.gov/pubmed/27695478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00164
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