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Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

BACKGROUND: The advent of whole-genome sequencing has generated increased interest in modelling the structure of strain mixture within clinical infections of Plasmodium falciparum The life cycle of the parasite implies that the mixture of multiple strains within an infected individual is related to...

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Vydáno v:Malar J
Hlavní autoři: O’Brien, John D., Amenga-Etego, Lucas, Li, Ruiqi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025560/
https://ncbi.nlm.nih.gov/pubmed/27634595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1531-z
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