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Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data
We present a rigorous statistical model that infers the structure of P. falciparum mixtures—including the number of strains present, their proportion within the samples, and the amount of unexplained mixture—using whole genome sequence (WGS) data. Applied to simulation data, artificial laboratory mi...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4928962/ https://ncbi.nlm.nih.gov/pubmed/27362949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004824 |
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