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DNA Methylome Analyses Implicate Fallopian Tube Epithelia as the Origin for High-grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSC) is the most common and lethal form of epithelial ovarian cancer (EOC). Two distinct tissues have been suggested as the tissue of origin: ovarian surface epithelia (OSE) and fallopian tube epithelia (FTE). We hypothesized that the DNA methylome of HGSC should m...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Klinkebiel, David, Zhang, Wa, Akers, Stacey, Odunsi, Kunle, Karpf, Adam R.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025356/
https://ncbi.nlm.nih.gov/pubmed/27259716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0097
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