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Nodal promotes invasive phenotypes via a Mitogen Activated Protein Kinase-dependent pathway

The progression of cancer from localized to invasive disease is requisite for metastasis, and is often characterized by epithelial-to-mesenchymal transition (EMT) and alterations in cellular adhesion and migration. Studies have shown that this transition is associated with an up-regulation of embryo...

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Bibliographic Details
Published in:Oncogene
Main Authors: Quail, DF, Zhang, G, Findlay, SD, Hess, DA, Postovit, LM
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025281/
https://ncbi.nlm.nih.gov/pubmed/23334323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.608
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