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Sox4 Mediated Dicer Expression is Critical for Suppression of Melanoma Cell Invasion

We previously reported reduced expression of Sox4 in metastatic melanoma and its role in suppression of cell migration and invasion through inhibition of NF-κB p50. Sox4 can also bind to the promoter sequence of Dicer, a miRNA biogenesis factor. Interestingly, altered expression of Dicer was also ob...

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Bibliographic Details
Published in:Oncogene
Main Authors: Jafarnejad, Seyed Mehdi, Ardekani, Gholamreza Safaee, Ghaffari, Mazyar, Martinka, Magdalena, Li, Gang
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025280/
https://ncbi.nlm.nih.gov/pubmed/22689055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.239
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