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Pharmacometabonomic prediction of busulfan clearance in hematopoietic cell transplant recipients

Intravenous (IV) busulfan doses are often personalized to a concentration at steady state (Css) using the patient’s clearance, which is estimated with therapeutic drug monitoring. We sought to identify biomarkers of IV busulfan clearance using a targeted pharmacometabonomics approach. A total of 200...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Navarro, Sandi L., Randolph, Timothy W., Shireman, Laura M., Raftery, Daniel, McCune, Jeannine S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025252/
https://ncbi.nlm.nih.gov/pubmed/27350098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00370
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