Prediction of Intravenous Busulfan Clearance by Endogenous Plasma Biomarkers Using Global Pharmacometabolomics

INTRODUCTION: High-dose busulfan (busulfan) is an integral part of the majority of hematopoietic cell transplantation conditioning regimens. Intravenous (IV) busulfan doses are personalized using pharmacokinetics (PK)-based dosing where the patient’s IV busulfan clearance is calculated after the fir...

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Bibliografske podrobnosti
izdano v:Metabolomics
Main Authors: Lin, Yvonne S., Kerr, Savannah J., Randolph, Timothy, Shireman, Laura M., Senn, Tauri, McCune, Jeannine S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562150/
https://ncbi.nlm.nih.gov/pubmed/28827982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1106-6
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