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KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation

Systemic inflammatory response syndrome (SIRS) is a form of fatal acute inflammation for which there is no effective treatment. Here, we revealed that the ablation of Kelch domain containing 10 (KLHDC10), which we had originally identified as an activator of Apoptosis Signal-regulating Kinase 1 (ASK...

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Veröffentlicht in:PLoS One
Hauptverfasser: Yamaguchi, Namiko, Sekine, Shiori, Naguro, Isao, Sekine, Yusuke, Ichijo, Hidenori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025154/
https://ncbi.nlm.nih.gov/pubmed/27631783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163118
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