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The Contribution of Mosaic Variants to Autism Spectrum Disorder

De novo mutation is highly implicated in autism spectrum disorder (ASD). However, the contribution of post-zygotic mutation to ASD is poorly characterized. We performed both exome sequencing of paired samples and analysis of de novo variants from whole-exome sequencing of 2,388 families. While we fi...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Freed, Donald, Pevsner, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024993/
https://ncbi.nlm.nih.gov/pubmed/27632392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006245
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