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Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability

[Image: see text] There is a compelling and growing need to accurately predict the impact of amino acid mutations on protein stability for problems in personalized medicine and other applications. Here the ability of 10 computational tools to accurately predict mutation-induced perturbation of foldi...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Kroncke, Brett M., Duran, Amanda M., Mendenhall, Jeffrey L., Meiler, Jens, Blume, Jeffrey D., Sanders, Charles R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2016
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024705/
https://ncbi.nlm.nih.gov/pubmed/27564391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00537
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