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What have single-molecule studies taught us about gene expression?

The production of a single mRNA is the result of many sequential steps, from docking of transcription factors to polymerase initiation, elongation, splicing, and, finally, termination. Much of our knowledge about the fundamentals of RNA synthesis and processing come from ensemble in vitro biochemica...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Chen, Huimin, Larson, Daniel R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024679/
https://ncbi.nlm.nih.gov/pubmed/27601529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.281725.116
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