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Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes

The transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal body and the axoneme that regulates ciliary traffic. Mutations in genes encoding TZ proteins (TZPs) cause human inherited diseases (ciliopathies). Here, we use the trypanosome to identify TZ comp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dean, Samuel, Moreira-Leite, Flavia, Varga, Vladimir, Gull, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024643/
https://ncbi.nlm.nih.gov/pubmed/27519801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604258113
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