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Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes

The transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal body and the axoneme that regulates ciliary traffic. Mutations in genes encoding TZ proteins (TZPs) cause human inherited diseases (ciliopathies). Here, we use the trypanosome to identify TZ comp...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Dean, Samuel, Moreira-Leite, Flavia, Varga, Vladimir, Gull, Keith
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024643/
https://ncbi.nlm.nih.gov/pubmed/27519801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604258113
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