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Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes

The transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal body and the axoneme that regulates ciliary traffic. Mutations in genes encoding TZ proteins (TZPs) cause human inherited diseases (ciliopathies). Here, we use the trypanosome to identify TZ comp...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Dean, Samuel, Moreira-Leite, Flavia, Varga, Vladimir, Gull, Keith
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024643/
https://ncbi.nlm.nih.gov/pubmed/27519801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604258113
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