Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

Tumor relapse after chemotherapy-induced regression is a major clinical problem, because it often involves inoperable metastatic disease. Tumor-associated macrophages (TAM) are known to limit the cytotoxic effects of chemotherapy in preclinical models of cancer. Here, we report that an alternatively...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Hughes, Russell, Qian, Bin-Zhi, Rowan, Charlotte, Muthana, Munitta, Keklikoglou, Ioanna, Olson, Oakley C., Tazzyman, Simon, Danson, Sarah, Addison, Christina, Clemons, Mark, Gonzalez-Angulo, Ana Maria, Joyce, Johanna A., De Palma, Michele, Pollard, Jeffrey W., Lewis, Claire E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024531/
https://ncbi.nlm.nih.gov/pubmed/26269531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3587
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