A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo

The androgen receptor plays a critical role in the progression of prostate cancer. Here, we describe targeting the prostate-specific membrane antigen using a lipid nanoparticle formulation containing small interfering RNA designed to silence expression of the messenger RNA encoding the androgen rece...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Nucleic Acids
Asıl Yazarlar: Lee, Justin B, Zhang, Kaixin, Tam, Yuen Yi C, Quick, Joslyn, Tam, Ying K, Lin, Paulo JC, Chen, Sam, Liu, Yan, Nair, Jayaprakash K, Zlatev, Ivan, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Rennie, Paul S, Cullis, Pieter R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024509/
https://ncbi.nlm.nih.gov/pubmed/28131285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.43
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