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Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models
Mammalian sperm acquire fertilizing capacity in the female tract in a process called capacitation. At the molecular level, capacitation requires protein kinase A activation, changes in membrane potential and an increase in intracellular calcium. Inhibition of these pathways results in loss of fertil...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024339/ https://ncbi.nlm.nih.gov/pubmed/27627854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33589 |
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