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Unique roles of the unfolded protein response pathway in fungal development and differentiation

Cryptococcus neoformans, a global fungal meningitis pathogen, employs the unfolded protein response pathway. This pathway, which consists of an evolutionarily conserved Ire1 kinase/endoribonuclease and a unique transcription factor (Hxl1), modulates the endoplasmic reticulum stress response and path...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jung, Kwang-Woo, So, Yee-Seul, Bahn, Yong-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024300/
https://ncbi.nlm.nih.gov/pubmed/27629591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33413
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