SELMAP - SELEX affinity landscape MAPping of transcription factor binding sites using integrated microfluidics

Transcription factors (TFs) alter gene expression in response to changes in the environment through sequence-specific interactions with the DNA. These interactions are best portrayed as a landscape of TF binding affinities. Current methods to study sequence-specific binding preferences suffer from l...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Chen, Dana, Orenstein, Yaron, Golodnitsky, Rada, Pellach, Michal, Avrahami, Dorit, Wachtel, Chaim, Ovadia-Shochat, Avital, Shir-Shapira, Hila, Kedmi, Adi, Juven-Gershon, Tamar, Shamir, Ron, Gerber, Doron
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024299/
https://ncbi.nlm.nih.gov/pubmed/27628341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33351
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares