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Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion

Effective therapeutic measures against the development of brain edema, a life-threatening complication of cerebral ischemia, are necessary to improve the functional outcome for the patient. Here, we identified a beneficial role of purinergic receptor P2X7 activation in acute ischemic stroke. Involve...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Kaiser, Melanie, Penk, Anja, Franke, Heike, Krügel, Ute, Nörenberg, Wolfgang, Huster, Daniel, Schaefer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023626/
https://ncbi.nlm.nih.gov/pubmed/27048203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9511-x
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