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Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice
Brain edema is an important pathological process during stroke. Activation of transient receptor potential vanilloid 4 (TRPV4) causes an up-regulation of matrix metalloproteinases (MMPs) in lung tissue. MMP can digest the endothelial basal lamina to destroy blood brain barrier, leading to vasogenic...
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| Vydáno v: | Front Cell Neurosci |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392311/ https://ncbi.nlm.nih.gov/pubmed/25914628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00141 |
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