Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice

Brain edema is an important pathological process during stroke. Activation of transient receptor potential vanilloid 4 (TRPV4) causes an up-regulation of matrix metalloproteinases (MMPs) in lung tissue. MMP can digest the endothelial basal lamina to destroy blood brain barrier, leading to vasogenic...

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Dades bibliogràfiques
Publicat a:Front Cell Neurosci
Autors principals: Jie, Pinghui, Tian, Yujing, Hong, Zhiwen, Li, Lin, Zhou, Libin, Chen, Lei, Chen, Ling
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392311/
https://ncbi.nlm.nih.gov/pubmed/25914628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00141
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