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Small Molecular TRAIL Inducer ONC201 Induces Death in Lung Cancer Cells: A Preclinical Study

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively targets cancer cells. The present preclinical study investigated the anti-cancer efficiency of ONC201, a first-in-class small molecule TRAIL inducer, in lung cancer cells. We showed that ONC201 was cytotoxic and anti-p...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Feng, Yuan, Zhou, Jihong, Li, Zhanhua, Jiang, Ying, Zhou, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023178/
https://ncbi.nlm.nih.gov/pubmed/27626799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162133
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