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The pharmacogenomics of drug resistance to protein kinase inhibitors
Dysregulation of growth factor cell signaling is a major driver of most human cancers. This has led to development of numerous drugs targeting protein kinases, with demonstrated efficacy in the treatment of a wide spectrum of cancers. Despite their high initial response rates and survival benefits,...
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| Publicat a: | Drug Resist Updat |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5022787/ https://ncbi.nlm.nih.gov/pubmed/27620953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2016.06.008 |
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