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The pharmacogenomics of drug resistance to protein kinase inhibitors

Dysregulation of growth factor cell signaling is a major driver of most human cancers. This has led to development of numerous drugs targeting protein kinases, with demonstrated efficacy in the treatment of a wide spectrum of cancers. Despite their high initial response rates and survival benefits,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Resist Updat
Main Authors: Gillis, Nancy K., McLeod, Howard L.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022787/
https://ncbi.nlm.nih.gov/pubmed/27620953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2016.06.008
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