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A novel phosphorylation site at Ser(130) adjacent to the pseudosubstrate domain contributes to the activation of protein kinase C-δ
Protein kinase C-δ (PKCδ) is a signalling kinase that regulates many cellular responses. Although most studies focus on allosteric mechanisms that activate PKCδ at membranes, PKCδ also is controlled via multi-site phosphorylation [Gong et al. (2015) Mol. Cell. Biol. 35, 1727–1740]. The present study...
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| Publicado en: | Biochem J |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5022567/ https://ncbi.nlm.nih.gov/pubmed/26546672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150812 |
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