P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons

Plasticity at excitatory synapses can be induced either by synaptic release of glutamate or the release of gliotransmitters such as ATP. Recently, we showed that postsynaptic P2X2 receptors activated by ATP released from astrocytes downregulate synaptic AMPAR, providing a novel mechanism by which gl...

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Vydáno v:Sci Rep
Hlavní autoři: Pougnet, Johan-Till, Compans, Benjamin, Martinez, Audrey, Choquet, Daniel, Hosy, Eric, Boué-Grabot, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022001/
https://ncbi.nlm.nih.gov/pubmed/27624155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31836
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