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An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Hua, Hong-Li, Zhang, Fa-Zhan, Labena, Abraham Alemayehu, Dong, Chuan, Jin, Yan-Ting, Guo, Feng-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021884/
https://ncbi.nlm.nih.gov/pubmed/27660763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7639397
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