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An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Hua, Hong-Li, Zhang, Fa-Zhan, Labena, Abraham Alemayehu, Dong, Chuan, Jin, Yan-Ting, Guo, Feng-Biao
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021884/
https://ncbi.nlm.nih.gov/pubmed/27660763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7639397
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