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An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Hua, Hong-Li, Zhang, Fa-Zhan, Labena, Abraham Alemayehu, Dong, Chuan, Jin, Yan-Ting, Guo, Feng-Biao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021884/
https://ncbi.nlm.nih.gov/pubmed/27660763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7639397
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