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An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms

Investigation of essential genes is significant to comprehend the minimal gene sets of cell and discover potential drug targets. In this study, a novel approach based on multiple homology mapping and machine learning method was introduced to predict essential genes. We focused on 25 bacteria which h...

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Podrobná bibliografie
Vydáno v:Biomed Res Int
Hlavní autoři: Hua, Hong-Li, Zhang, Fa-Zhan, Labena, Abraham Alemayehu, Dong, Chuan, Jin, Yan-Ting, Guo, Feng-Biao
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021884/
https://ncbi.nlm.nih.gov/pubmed/27660763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7639397
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