Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

Osteopontin (OPN) is associated with the severity and progression of osteoarthritis (OA); however, the mechanism of OPN in the pathogenesis of OA is unknown. In this study, we found that OA patients had higher abundance of OPN and matrix metalloproteinase 13 (MMP13). In chondrocytes, we showed that...

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Bibliografski detalji
Izdano u:Biomed Res Int
Glavni autori: Li, Yusheng, Jiang, Wei, Wang, Hua, Deng, Zhenhan, Zeng, Chao, Tu, Min, Li, Liangjun, Xiao, Wenfeng, Gao, Shuguang, Luo, Wei, Lei, Guanghua
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021466/
https://ncbi.nlm.nih.gov/pubmed/27656654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6345656
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