Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

Osteopontin (OPN) is associated with the severity and progression of osteoarthritis (OA); however, the mechanism of OPN in the pathogenesis of OA is unknown. In this study, we found that OA patients had higher abundance of OPN and matrix metalloproteinase 13 (MMP13). In chondrocytes, we showed that...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomed Res Int
Päätekijät: Li, Yusheng, Jiang, Wei, Wang, Hua, Deng, Zhenhan, Zeng, Chao, Tu, Min, Li, Liangjun, Xiao, Wenfeng, Gao, Shuguang, Luo, Wei, Lei, Guanghua
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021466/
https://ncbi.nlm.nih.gov/pubmed/27656654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6345656
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