Modification of Three Amino Acids in Sodium Taurocholate Cotransporting Polypeptide Renders Mice Susceptible to Infection with Hepatitis D Virus In Vivo

Sodium taurocholate cotransporting polypeptide (NTCP) was identified as a functional receptor for hepatitis D virus (HDV) and its helper hepatitis B virus (HBV). In cultured cell lines, HDV infection through mouse NTCP is restricted by residues 84 to 87 of the receptor. This study shows that mice wi...

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Vydáno v:J Virol
Hlavní autoři: He, Wenhui, Cao, Zhiliang, Mao, Fengfeng, Ren, Bijie, Li, Yunfei, Li, Dan, Li, Huiyu, Peng, Bo, Yan, Huan, Qi, Yonghe, Sun, Yinyan, Wang, Fengchao, Sui, Jianhua, Li, Wenhui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021397/
https://ncbi.nlm.nih.gov/pubmed/27466423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00901-16
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