Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency

Sodium taurocholate cotransporting polypeptide (NTCP, encoded by Slc10a1/SLC10A1) deficiency can result in hypercholanemia but no obvious symptoms in both mice and humans. However, the consequence of and response to long-term hypercholanemia caused by NTCP deficiency remain largely unexplored. Here,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mao, Fengfeng, Liu, Teng, Hou, Xinfeng, Zhao, Hanqing, He, Wenhui, Li, Cong, Jing, Zhiyi, Sui, Jianhua, Wang, Fengchao, Liu, Xiaohui, Han, Jun, Borchers, Christoph H., Wang, Jian-She, Li, Wenhui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682732/
https://ncbi.nlm.nih.gov/pubmed/31201272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007179
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