Transcriptional Modulator Ifrd1 Regulates Osteoclast Differentiation through Enhancing the NF-κB/NFATc1 Pathway

Bone homeostasis is maintained by the synergistic actions of bone-resorbing osteoclasts and bone-forming osteoblasts. Here, we show that the transcriptional coactivator/repressor interferon-related developmental regulator 1 (Ifrd1) is expressed in osteoclast lineages and represents a component of th...

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Pubblicato in:Mol Cell Biol
Autori principali: Iezaki, Takashi, Fukasawa, Kazuya, Park, Gyujin, Horie, Tetsuhiro, Kanayama, Takashi, Ozaki, Kakeru, Onishi, Yuki, Takahata, Yoshifumi, Nakamura, Yukari, Takarada, Takeshi, Yoneda, Yukio, Nakamura, Takashi, Vacher, Jean, Hinoi, Eiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021375/
https://ncbi.nlm.nih.gov/pubmed/27381458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01075-15
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