The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice

BACKGROUND AND PURPOSE: Although naturally occurring polyamines are indispensable for a variety of cellular events in eukaryotic cells, little attention has been paid to their physiological and pathological significance in bone remodelling to date. In this study, we evaluated the pharmacological pro...

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Autores principales: Yamamoto, Tomomi, Hinoi, Eiichi, Fujita, Hiroyuki, Iezaki, Takashi, Takahata, Yoshifumi, Takamori, Misa, Yoneda, Yukio
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417431/
https://ncbi.nlm.nih.gov/pubmed/22250848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01856.x
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