The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice

BACKGROUND AND PURPOSE: Although naturally occurring polyamines are indispensable for a variety of cellular events in eukaryotic cells, little attention has been paid to their physiological and pathological significance in bone remodelling to date. In this study, we evaluated the pharmacological pro...

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Detalhes bibliográficos
Main Authors: Yamamoto, Tomomi, Hinoi, Eiichi, Fujita, Hiroyuki, Iezaki, Takashi, Takahata, Yoshifumi, Takamori, Misa, Yoneda, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417431/
https://ncbi.nlm.nih.gov/pubmed/22250848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01856.x
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