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Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH

TFIIH is a 10-subunit RNA polymerase II basal transcription factor with a dual role in DNA repair. TFIIH contains three enzymatic functions and over 30 conserved subdomains and topological regions. We systematically tested the function of these regions in three TFIIH core module subunits, i.e., Ssl1...

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Publicat a:Mol Cell Biol
Autors principals: Warfield, Linda, Luo, Jie, Ranish, Jeffrey, Hahn, Steven
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021372/
https://ncbi.nlm.nih.gov/pubmed/27381459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00182-16
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