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Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH

TFIIH is a 10-subunit RNA polymerase II basal transcription factor with a dual role in DNA repair. TFIIH contains three enzymatic functions and over 30 conserved subdomains and topological regions. We systematically tested the function of these regions in three TFIIH core module subunits, i.e., Ssl1...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Warfield, Linda, Luo, Jie, Ranish, Jeffrey, Hahn, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021372/
https://ncbi.nlm.nih.gov/pubmed/27381459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00182-16
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