Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand

Delta/Notch-like EGF-related receptor (DNER) has been reported to act as a Notch ligand, despite lacking a Delta/Serrate/Lag (DSL) binding domain common to all other known ligands. The established Notch ligand Delta-like 1 (DLL1), but not DNER, activated Notch1 in a luciferase assay, prevented the d...

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Publicat a:PLoS One
Autors principals: Greene, Maxwell, Lai, Yongjie, Pajcini, Kostandin, Bailis, Will, Pear, Warren S., Lancaster, Eric
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021350/
https://ncbi.nlm.nih.gov/pubmed/27622512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161157
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