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Diastereoselective syntheses of substituted cis-hydrindanones featuring sequential inter- and intramolecular Michael reactions

The hydrindane (bicyclo[4.3.0]nonane) structural motif (1) and related cis-1-hydrindanone skeleton (2) are common substructures in many natural products. Herein, we describe efficient access to substituted cis-1-hydrindanones enabled by a sequence of Michael reactions. A copper-catalyzed intermolecu...

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Detalhes bibliográficos
Publicado no:Tetrahedron
Main Authors: Liu, Junjia, Marsini, Maurice A., Bedell, T. Aaron, Reider, Paul J., Sorensen, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021295/
https://ncbi.nlm.nih.gov/pubmed/27642195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2016.03.039
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