Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis

Simultaneous multiplex mutation of large gene families using Cas9 has the potential to revolutionize agriculture and plant sciences. The targeting of multiple genomic sites at once raises concerns about the efficiency and specificity in targeting. The model Arabidopsis thaliana is widely used in bas...

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Publicado en:PLoS One
Main Authors: Peterson, Brenda A., Haak, David C., Nishimura, Marc T., Teixeira, Paulo J. P. L., James, Sean R., Dangl, Jeffery L., Nimchuk, Zachary L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021288/
https://ncbi.nlm.nih.gov/pubmed/27622539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162169
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