Metal-binding chimeric antibodies expressed in Escherichia coli.
Metallothionein, a well-characterized biological chelator of metals, has been genetically fused to the binding domain of an antibody and expressed in the periplasm of Escherichia coli. Specific delivery of 109Cd to immobilized hapten or to haptenated cells was demonstrated directly in periplasmic ex...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1992
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9754 |
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