Metal-binding chimeric antibodies expressed in Escherichia coli.
Metallothionein, a well-characterized biological chelator of metals, has been genetically fused to the binding domain of an antibody and expressed in the periplasm of Escherichia coli. Specific delivery of 109Cd to immobilized hapten or to haptenated cells was demonstrated directly in periplasmic ex...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50211/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9754 |
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