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Nek2 siRNA therapy using a portal venous port–catheter system for liver metastasis in pancreatic cancer

Nek2 (NIMA‐related kinase 2) is a serine‐threonine kinase and human homolog of the mitotic regulator NIMA of Aspergillus nidulan. We reported the efficiency of Nek2 siRNA in several cancer xenograft models using cholangiocarcinoma, breast cancer and colorectal cancer. Pancreatic cancer is difficult...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kokuryo, Toshio, Hibino, Shigeru, Suzuki, Kazushi, Watanabe, Katsutaka, Yokoyama, Yukihiro, Nagino, Masato, Senga, Takeshi, Hamaguchi, Michinari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021025/
https://ncbi.nlm.nih.gov/pubmed/27316377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12993
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